Written by DAVID HINE & FABRICE SAPOLSKY
Penciled by CARMINE DI GIANDOMENICO
Variant by DENNIS CALERO
The brutal and relentless Crime Master is the least of the Spider-Man's concerns! As the bloody wave of violent crime spreads across the city, Peter Parker discovers the greater monster is the eminent biologist, Dr. Otto Octavius! If Spider-Man lives to escape the grisly clutches of New York's most dangerous killer, will he survive a final encounter against the heartless, death-dealing scientist?